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N-[(2R,3S)-1-((2S)-2-{[(cyclopentylamino)carbonyl]amino}-3-methylbutanoyl)-2-(1-formyl-1-cyclobutyl)pyrrolidinyl]cyclopropanecarboxamide

Development stage
Preclinical
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule with the molecular formula C24H38N4O4 and a molecular weight of approximately 446.6 g/mol. It is classified as an experimental pharmaceutical and belongs to the class of n-carbamoyl-alpha amino acids and derivatives[1][2]. The compound has been studied as an inhibitor of the NS3 protease from Hepatitis C Virus (HCV), which is essential for viral replication. By inhibiting this serine protease, it may block viral polyprotein processing and thus HCV replication[4][2]. There are no approved indications or marketed products containing this molecule; it remains primarily a research tool or lead structure in antiviral drug discovery.

Other names
N-((2R,3S)-1-((2S)-2-(((Cyclopentylamino)carbonyl)amino)-3-methylbutanoyl)-2-(1-formyl-1-cyclobutyl)pyrrolidinyl)cyclopropanecarboxamideN-((2R,3S)-1-((2S)-2-((cyclopentylcarbamoyl)amino)-3-methylbutanoyl)-2-(1-formylcyclobutyl)pyrrolidin-3-yl)cyclopropanecarboxamideN-[(2R,3S)-1-[(2S)-2-{(cyclopentylcarbamoyl)amino]-3-methylbutanoyl]-2-(1-formylcyclobutyl)pyrrolidin–3– yl] cyclopropane carboxamide
02

Targets

NS3/4A (Hepatitis C virus nonstructural protein 3/4A serine protease)

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